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Publications

  • Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development
    Scherer et al (including Alessandro Greco ESR2, Thomas Hoefer, Dietmar Zehn)
    Nature Communications, 24, pages 501–515 (2023)
    https://doi.org/10.1038/s41590-023-01436-x
  • Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells
    Sacirbegovic et al (including Alessandro Greco ESR2, Thomas Hoefer)
    Immunity, 2023, Vol.56 (2), p.369-385.e6
    https://doi.org/10.1016/j.immuni.2023.01.003
  • KIR-HLA interactions extend human CD8+ T cell lifespan in vivo
    Zhang et al (including Laura Mora Bitria ESR12, Becca Asquith)
    Journal of Clinical Investigation, 2023;133(12):e169496
    https://doi.org/10.1172/JCI169496
  • COGNITION: a prospective precision oncology trial for patients with early breast cancer at high risk following neoadjuvant chemotherapy
    Pixberg et al (including Sarah Benedetto ESR1, Thomas Hoefer)
    ESMO Open, volume 7, issue 6, 100637, December 2022
    https://doi.org/10.1016/j.esmoop.2022.100637
  • Lineage tracing reveals B cell antibody class switching is stochastic, cell-autonomous, and tuneable
    Miles B. Horton, HoChan Cheon (ESR15), Ken R. Duffy, Daniel Brown, Shalin H. Naik, Carolina Alvarado, Joanna R. Groom, Susanne Heinzel, Philip D. Hodgkin
    Immunity volume 55, Issue 10, 11 October 2022, Pages 1843-1855.e6
    https://doi.org/10.1016/j.immuni.2022.08.004
  • Modeling and predicting the overlap of B- and T-cell receptor repertoires in healthy and SARS-CoV-2 infected individuals
    Maria Ruiz Ortega (ESR11), Natanael Spisak, Thierry Mora, Aleksandra M. Walczak
    PLOS Genetics 19 (2), e1010652
    https://doi.org/10.1371/journal.pgen.1010652
  • Comparison of blood and lymph node cells after intramuscular injection with HIV envelope immunogens
    Day et al (including Charandeep Kaur ESR5, Becca Asquith)
    Frontiers in Immunology  13:991509
    https://doi.org/10.3389/fimmu.2022.991509
  • Innate receptors modulating adaptive T cell responses: KIR-HLA interactions and T cell-mediated control of chronic viral infections
    Laura Mora-Bitria (ESR12) & Becca Asquith
    Immunogenetics 75, 269–282 (2023)
    https://doi.org/10.1007/s00251-023-01293-w
  • Why are cell populations maintained via multiple compartments?
    Flavia Feliciangeli (ESR13), Hanan Dreiwi, Martín López-García, Mario Castro Ponce, Carmen Molina-París and Grant Lythe
    Journal of the Royal Society Interface 19: 20220629
    https://doi.org/10.1098/rsif.2022.0629
  • Fate mapping of hematopoietic stem cells reveals two pathways of native thrombopoiesis
    Morcos et al (including Alessandro Greco ESR2, Thomas Höfer)
    Nature Communications 13, 4504 (2022)
    https://doi.org/10.1038/s41467-022-31914-z
  • Counting generations in birth and death processes with competing Erlang and exponential waiting times
    Giulia Belluccini (ESR6), Martín López‑García, Grant Lythe & Carmen Molina‑París
    Scientific Reports, 2022, 12:11289
    https://doi.org/10.1038/s41598-022-14202-0
  • Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model
    Simovic et al (including Sarah Benedetto ESR1, Thomas Höfer)
    Neuro-Oncology Volume 23, Issue 12, December 2021, Pages 2028–2041
    https://doi.org/10.1093/neuonc/noab127
  • Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARSCoV-2 antibody response
    Lin et al (including Daniel Luque Duque ESR10, Carmen Molina-Paris, Paul Thomas)
    Cell Host and Microbe, 2021, volume 30, issue 1, P83-96.E4
    https://doi.org/10.1016/j.chom.2021.12.005
  • RBM-MHC: A Semi-Supervised Machine-Learning Method for Sample-Specific Prediction of Antigen Presentation by HLA-I Alleles
    Barbara Bravi, Jérôme Tubiana, Simona Cocco, Rémi Monasson, Thierry Mora, Aleksandra M.Walczak
    Cell Systems, 2021, Volume 12, Issue 2, Pages 195-202.e9
    https://doi.org/10.1016/j.cels.2020.11.005
  • Cyton2: A Model of Immune Cell Population Dynamics That Includes Familial Instructional Inheritance
    HoChan Cheon (ESR15), Andrey Kan, Giulio Prevedello, Simone Oostindie, Simon Dovedi, Edwin Hawkins, Julia Marchingo, Susanne Heinzel, Ken Duffy and Philip Hodgkin
    Frontiers in Bioinformatics, 2021
    https://doi.org/10.3389/fbinf.2021.723337
  • Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses
    Wilmes et al (including Grant Lythe, Carmen Molina-París)
    eLife 2021, 10:e66014
    https://doi.org/10.7554/eLife.66014
  • No evidence that HLA genotype influences the driver mutations that occur in cancer patients
    Noor Kherreh (ESR9), Siobhán Cleary & Cathal Seoighe
    Cancer Immunology, Immunotherapy, 2021
    https://doi.org/10.1007/s00262-021-03028-w
  • Step-by-step comparison of ordinary differential equation and agent-based approaches to pharmacokinetic-pharmacodynamic models
    Van Thuy Truong (ESR14), Paul G. Baverel, Grant D. Lythe, Paolo Vicini, James W. T. Yates, Vincent F. S. Dubois
    CPT: Pharmacometrics + Systems Pharmacology, 2021
    https://doi.org/10.1002/psp4.12703
  • Quantifying T Cell Cross-Reactivity: Influenza and Coronaviruses
    Jessica Gaevert, Daniel Luque Duque (ESR 10), Grant Lythe, Carmen Molina-París, Paul Thomas
    Viruses 2021, 13(9), 1786
    https://doi.org/10.3390/v13091786
  • Stochastic modelling of the T cell repertoire with epitope affinity
    Daniel F Luque Duque (ESR 10), Carmen Molina-Paris, Grant Lythe, Martin Lopez Garcia, Paul Thomas and Jessica Gaevert
    Journal of Immunology vol. 204 no. 1 Supplement 94.18" Published online May 19, 2020.
    (Abstract submitted for the AAI Conference 2020)
    https://doi.org/10.4049/jimmunol.204.Supp.94.18
  • Resolving Fates and Single-Cell Transcriptomes of Hematopoietic Stem Cell Clones by PolyloxExpress Barcoding
    Weike Pei et al (including Alessandro Greco (ESR 2), Thomas Höfer, Hans-Reimer Rodewald)
    Cell Stem Cell Volume 27, issue 3, p383-395, 3 Sept 2020
    https://doi.org/10.1016/j.stem.2020.07.018
  • Using Cre-recombinase-driven Polyloxbarcoding for in vivo fate mapping in mice
    Weike Pei, Xi Wang, Jens Rössler, Thorsten B. Feyerabend, Thomas Höfer & Hans-Reimer Rodewald
    Nature Protocols 14, 1820–1840 (2019)
    https://doi.org/10.1038/s41596-019-0163-5
  • IL7 receptor signaling in T cells: A mathematical modeling perspective
    Jung-Hyun Park, Adam T. Waickman, Joseph Reynolds, Mario Castro, Carmen Molina-París
    WIREs Systems Biology and Medicine 11:e1447 (2019)
    https://doi.org/10.1002/wsbm.1447
  • Fate of a Naive T Cell: A Stochastic Journey
    Luis de la Higuera, Martín López-García, Mario Castro, Niloufar Abourashchi, Grant Lythe and Carmen Molina-París
    Frontiers in Immunology, 10:194 (2019)
    https://doi.org/10.3389/fimmu.2019.00194