WP1 - Compartmentalisation and dynamics of T cells

This WP requires a combination of novel experimental techniques and modelling (deterministic and stochastic) approaches, and thus mathematicians (B1, B2, B8) and experimental immunologists (B5 and B8) will work closely together. The main objective is to quantify whole body compartmentalisation and kinetic rates of naive and memory T cells and develop suitable mathematical models.

WP2: TCR repertoires in health and disease in blood and tissues

WP3: T cell immunotherapies