- Email: firstname.lastname@example.org
- Location: DKFZ
- Supervisor: Thomas Höfer
- Project Title: Thymic T cell production and onset of acute T cell leukemia (theory)
Short description of my project:
The aim of my project is to understand the emergence of lymphocytes and lymphoid progenitors from hematopoietic stem cells, how this process is affected by challenges to the immune system, such as multimicrobial sepsis or irradiation and how tranformation to T cell leukemia can set it. To this end, I analyse the RNA of hematopoietic stem cells and progenitors at single cell resolution and at different timepoints, and reveal how the hematopoietic branching is affected over time.
In the video below, Alessandro discusses his research project and aim, and also how being part of the QuanTII network helps his PhD (the video was created at the Complementary Skills Workshop in Leeds):